Skip to main content
Cruise ship

8-night Lower Mississippi River Cruise

American Cruise Lines Logo
American Serenade
cruise info

  • American Cruise Lines: American Serenade
  • |
  • April 10, 2026

itinerary

  1. Day 1
    Memphis
    | Fri Apr 10, 2026
  2. Day 2
    Mississippi River Cruising
    | Sat Apr 11, 2026
  3. Day 3
    Cleveland
    | Sun Apr 12, 2026
  4. Day 4
    Vicksburg
    | Mon Apr 13, 2026
  5. Day 5
    Natchez
    | Tue Apr 14, 2026
  6. Day 6
    St. Francisville
    | Wed Apr 15, 2026
  7. Day 7
    River Cruising
    | Thu Apr 16, 2026
  8. Day 8
    Oak Alley Plantation
    | Fri Apr 17, 2026
  9. Day 9
    Houmas House
    | Fri Apr 17, 2026
  10. Day 10
    New Orleans
    | Sat Apr 18, 2026
Sailing Features
  • 8 Nights
  • Apr 10, 2026 / Apr 18, 2026
  • Memphis
  • New Orleans
  • American Serenade
Bonus Offers
Exclusive Amenities Available:
  • $100 per Couple Shipboard Credit

Suites

Choose the perfect room for you
Suite
Balcony
Suite
Grand Suite (Private Balcony)

The luxurious Grand Suite measures 650 sq. ft. and offers panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a private balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.

Suite
Veranda Suite (Private Balcony)

With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.

American Cruise Lines Expert Advisors

Connect with an Expert to personally walk you through this Itinerary
Travel Advisor Profile Picture

Roni Palacios

(520) 428-7714
Learn More ->
Travel Advisor Profile Picture

Thea Lawrence

(520) 232-5569
Learn More ->
Travel Advisor Profile Picture

Annette Holt

(520) 232-5519
Learn More ->
American Serenade cruise ship

American Cruise Lines:   American Serenade

American Serenade won Cruise Critic’s Editors’ Picks Award for Best New River Cruise Ship of the Year recently, the first time an American ship has received this prestigious award. Introduces an updated modern interior design, integrating an elegant and refined aesthetic with tradition for the spacious comfort found aboard all of ships Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.
  • Maiden Voyage:
    2023
  • Passenger Capacity:
    175
  • Number of Staterooms:
    91
  • Number of Suites:
    16
  • Wheelchair Accessible:
    Yes

Ship Information

Explore Your Cruise Ship
The colorfully painted beach houses of Slovenia as seen from a cave
Don't Miss Out on Any Trip Enhancing Shore Excursions!
Immerse yourself in local culture with authentic cooking classes, traditional dance lessons, and unforgettable visits to historical landmarks during your cruise shore excursions.
A beautiful wooden foyer with luxury seating and shelves filled with fine items
Extend Your Trip with Immersive Pre-Cruise or Post-Cruise Stays
Enjoy the local culture and savor delicious cuisine with pre-cruise or post-cruise stays, ensuring a seamless transition between your land and sea adventures.