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15 Nights - Pittsburgh To St. Louis

15-night Grand Ohio River Cruise

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American Melody
cruise info

15 Nights - Pittsburgh To St. Louis

  • American Cruise Lines: American Melody
  • |
  • August 15, 2025

itinerary

  1. Day 1
    Pittsburgh
    | Fri Aug 15, 2025
  2. Day 2
    Pittsburgh
    | Sat Aug 16, 2025
  3. Day 3
    At Sea
    | Sun Aug 17, 2025
  4. Day 4
    Marietta
    | Mon Aug 18, 2025
  5. Day 5
    At Sea
    | Tue Aug 19, 2025
  6. Day 6
    Maysville
    | Wed Aug 20, 2025
  7. Day 7
    Cincinnati
    | Thu Aug 21, 2025
  8. Day 8
    Madison
    | Fri Aug 22, 2025
  9. Day 9
    Louisville
    | Sat Aug 23, 2025
  10. Day 10
    At Sea
    | Sun Aug 24, 2025
  11. Day 11
    Henderson
    | Mon Aug 25, 2025
  12. Day 12
    Evansville
    | Mon Aug 25, 2025
  13. Day 13
    At Sea
    | Tue Aug 26, 2025
  14. Day 14
    Paducah
    | Wed Aug 27, 2025
  15. Day 15
    At Sea
    | Thu Aug 28, 2025
  16. Day 16
    St. Louis
    | Fri Aug 29, 2025
  17. Day 17
    St. Louis
    | Sat Aug 30, 2025
Sailing Features
  • 15 Nights
  • Aug 15, 2025 / Aug 30, 2025
  • Pittsburgh
  • St. Louis
  • American Melody
  • 17 Land Tours
Bonus Offers
Exclusive Amenities Available:
  • $100 per Couple Shipboard Credit

American Cruise Lines Expert Advisors

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Thea Lawrence

(520) 232-5569
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Mary Beth Preston

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Vicki Keune

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American Melody cruise ship

American Cruise Lines:   American Melody

The Future of American River Cruising™ continues with American Melody, the 4th in the modern riverboat series. American Melody showcases a whole new aesthetic, with an updated interior design, bringing ship to the next level of modern sophistication. Specifically designed to navigate the Mississippi River, American Melody features panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms feature full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. American Melody also offers the Ellipse Café for casual dining, an option that has been very popular with the guests.
  • Maiden Voyage:
    2021
  • Passenger Capacity:
    175
  • Number of Staterooms:
    91
  • Number of Suites:
    16
  • Dining / Restaurants:
    2
  • Bars / Lounges:
    4
  • Fitness Center:
    Yes
  • Lounge:
    Yes

Ship Information

Explore Your Cruise Ship

  • Dining

  • Bar & Lounges

  • Onboard Activities

  • Outdoor Activities

  • Wellness

The colorfully painted beach houses of Slovenia as seen from a cave
Don't Miss Out on Any Trip Enhancing Shore Excursions!
Immerse yourself in local culture with authentic cooking classes, traditional dance lessons, and unforgettable visits to historical landmarks during your cruise shore excursions.
A beautiful wooden foyer with luxury seating and shelves filled with fine items
Extend Your Trip with Immersive Pre-Cruise or Post-Cruise Stays
Enjoy the local culture and savor delicious cuisine with pre-cruise or post-cruise stays, ensuring a seamless transition between your land and sea adventures.